Endocrine Abstracts

Objective: Misclassification of type 1 (T1DM) and type 2 diabetes mellitus (T2DM) is quite common and crucial to choice of appropriate therapy. The aim of the study was to evaluate the correspondence of islet antigen-2 (Anti IA2) and glutamic acid decarboxylase (Anti GAD65) antibodies with clinical diagnosis.Methods: The Anti IA2 and Anti GAD65 were measured in 583 patients (337 males and 246 females) diagnosed with T1DM or T2DM with not typical manifest...

Background and aim: HLA alleles are associated with type 1 diabetes (T1D) and a spectrum of risk can be from increased to neutral or to protective. We aimed to evaluate the association of cardiovascular autonomic neuropathy (CAN) with DRB1* gene’s alleles among T1D.Methods: The case – control pilot study included 70 patients with T1D at the age 18-54 years. 36 patients with CAN were assigned to the case group and 34 patients without CAN – ...

Introduction: Stereotactic radiotherapy and more relevant pharmacotherapy are widely used for PA’s treatment; however transsphenoidal surgery remains gold standard. Postoperative complications and endocrinological outcomes vary widely and are related with surgeon experience and tumor characteristics.The aim of this study: To determine relationship between pituitary adenoma size and transsphenoidal pituitary adenoma surgery outcomes.<p class="abs...

Introduction: The number of studies on the incidence and outcomes of surgical treatment for pituitary adenomas is still limited, despite that pituitary tumours are one of the most frequent intracranial tumours.The aim of this study: To evaluate clinical features of transsphenoidaly operated pituitary adenomas (PA) and perioperative results of the treatment.Materials and methods: This is a retrospective single institution study of 4...